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OJVRTM

Online Journal of Veterinary Research©

 

Volume 23 (10):999-1004, 2019.


DNA clone encoding 34.9 kDa Carboxy terminal proline glutamic acid

protein of Mycobacterium avium paratuberculosis in E. Coli.

 

Deb R, Goswami PP, Prasad NS

                                          

Gene Expression Lab, Department of Animal Biotechnology,   Indian Veterinary Research Institute, Izatnagar, India

        

ABSTRACT

 

Deb R, Goswami PP, Prasad NS., DNA clone encoding 34.9 kDa Carboxy terminal proline glutamic acid  protein of Mycobacterium avium paratuberculosis in E. Coli., Onl J Vet Res., 23 (10):999-1006, 2019. Mycobacterium avium ssp. Paratuberculosis is the causative agent of Johne’s disease in animals. A  PPE (Proline Proline Glutamic acid rich) antigen encoding 34.9 kDa  hypothetical protein of M.avium subsp. Paratuberculosis was cloned and sequenced. Sequence analysis revealed that no other published sequences having significant homology with that PPE gene, suggesting that PPE 34.9- kDa could be used as a diagnostic antigen.

 

Key Words  PPE,  34.9 kDa,  Mycobacterium avium ssp. Paratuberculosis, FJ032182.


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