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OJVRTM

Online Journal of Veterinary Research©

 

Volume 19(4): 270-281, 2015.


Extraction of rumen α–amylase with cibacron blue magnetic nanoparticles

 

Nosrat Allah Ghazvini1, Mohammad Chamani1*, Homayon Ahmad Panahi2, Ali Asghar Sadeghi1 and Mehdi Aminafshar1

 

1 Department(s) of Animal Science, 2Chemistry, Faculty of Agriculture and Natural Resources, Tehran Science and Research Branch, Islamic Azad University, Tehran, Iran.

 

ABSTRACT

 

Ghazvini NA, Chamani M, PanahiHA, Sadeghi AA, Aminafshar M., Extraction of rumen α–amylase with cibacron blue magnetic nanoparticles, Onl J Vet Res., 19(4): 270-281, 2015. Magnetic nano-particles (MNPs) were grafted with allyl 2,3epoxypropyl ether and coupled with Cibacron blue ligand to capture α-amylase from clarified ruminal fluid. MNPs were analyzed by thermogravimetry, transmission electron microscopy, and Fourier transform infrared spectroscopy. Greatest adsorption efficiency occurred at pH 7, 24°C, and shaking time of 10 minutes. Most efficient desorption of absorbed active α-amylase occurred in 0.5 M NaCl solution for 90 minutes shaking (p<0.05). The results suggest that polymerization of Cibacron blue onto MNPs can extract rumen α-amylase. The purified α-amylase had high activity compared with native α-amylase.

 

Keywords: Amylase; Magnetic nanoparticles; Clarified rumen fluid; Adsorption; Desorption.


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