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OJVRTM

 

Online Journal of Veterinary Research

(Including Medical and Laboratory Research)

Established 1994

ISSN 1328-925X

 

Volume 28(7): 387-394, 2024.


Plasma and tissue cholinesterase in broilers gavaged dichlorvos and carbaryl

 

Fouad KM , Banan Al-Baggou

 

Department of Physiology, Biochemistry and Pharmacology, College of Veterinary Medicine, University of Mosul, Mosul, Iraq

 

Abstract

 

Fouad KM, Al-Baggou B., Plasma and tissue cholinesterase in broilers gavaged dichlorvos and carbaryl,, Onl J Vet Res.,  28(7): 387-394, 2024. We determined plasma, brain and liver cholinesterase in twenty one 45 days old broilers. Cholinesterase was measured in 0.2 ml plasma or tissue homogenate, 3ml distilled water, 3 ml pH 8.1 phosphate-barbital buffer and 0.12 ml 7.5% acetylthiocholine iodide substrate incubated 30min at 37 ˚C. Reference plasma enzyme values were 0.47 in brain, 0.25 and liver 0.21 ΔpH/30 min. Oral administration 7mg/kg dichlorvos and 100mg/kg carbamate reduced (P < 0.05) cholinesterase 62% in plasma 29% in brain and 28% in liver.

 

KEY-WORDS: Cholinesterase, broilers, dichlorvos, carbaryl.


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