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Online Journal of Veterinary Research

(Including Medical and Laboratory Research)

Established 1994
ISSN 1328-925X


Volume 25 (11):793-798, 2021.

Pathological and molecular study of high mortality canary pox viruses.


Vahid Reza Ranjbar1٭, Monire Khordadmehr2, Azizollah Khodakaram- Tafti2, Mehdi Namavari3


1Department(s) of Avian Medicine,2School of Veterinary Medicine, Shiraz University, 3Razi Vaccine and Serum Research Institute, Shiraz, Iran.




Ranjbar VR, Khordadmehr M, Khodakaram-Tafti A, Namavari M., Pathological and molecular study of high mortality canary pox viruses, Onl J Vet Res., 25 (11):793-798, 2021. Avian pox is caused by DNA in genus avipoxvirus. Canary poxvirus (CAPV) is one of 4 avian poxviruses. CAPV is highly infectious resulting in ~100% mortality in affected aviaries. We report an outbreak with 99% mortality in 200 color-breeder canaries in Yazd, Iran. Clinical signs prior to death were severe conjunctivitis, dyspnea, anorexia, weakness, rapid weight loss, fluffed-up appearance, cutaneous proliferative lesions around eyes and beak, and weakness of several days duration. By microscopy we found cutaneous ocular and beak lesions characterized by epidermal hypertrophy and hyperplasia, degeneration of stratified squamous epithelium and intracytoplasmic inclusions in hypertrophied epithelial cells of typical Bollinger bodies. In lungs we observed hyperemia, hemorrhages and fibrinous pneumonitis. By PCR we found 578 base pairs (bp) to confirm pox virus DNA in eyelids, skin and lung, but not in liver or heart.


Keywords: Pox virus, high mortality, lesions, PCR. Iran.