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OJBTM
Online Journal of
Bioinformatics ©
Volume 15 (2): 157-167, 2014
Finite element
model of calcium distribution in oocytes for one dimensional unsteady state
case
Parvaiz Ahmad Naik* and Kamal Raj Pardasani
Department of Mathematics, Maulana Azad
National Institute of Technology, Bhopal-462051, India.
ABSTRACT
Ahmad Naik P,
Pardasani KR., Finite element model of calcium
distribution in oocytes for one
dimensional unsteady state case, Onl J Bioinform., 15 (2): 157-167, 2014. Ca2+ is the second
messenger responsible for Oocyte maturation. The mechanisms involved in calcium
dynamics of oocyte maturation are poorly understood. In this paper an attempt
has been made to develop a model to estimate intracellular calcium
concentration in circular shaped oocyte. Essential parameters such as buffers,
influx and diffusion coefficient are incorporated in the model. Appropriate
initial and boundary conditions are framed. The finite element method has been
employed to solve the initial boundary value problem. The effect of buffers,
influx and diffusion coefficient on calcium concentration in oocyte has been resolved
with numerical results.
Keywords: Finite Element
Method, MATLAB, Buffers, Diffusion Coefficient, Reaction Diffusion Equations.