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Online Journal of Veterinary Research

Volume 23 (4):262-267, 2019.

Bromocriptine and cabergoline for induction of estrus in dogs.


Saif-Aldeen Abdal-Hadi Nawaf and Najlaa Sami Ibrahim.


Department of Surgery and Obstetrics, College of Veterinary Medicine, University of Baghdad, Iraq.




Abdal-Hadi Nawaf SA, Ibrahim NS., Bromocriptine versus cabergoline estrus induction in dogs., Onl J Vet Res., 23 (4):262-267, 2019. Twenty anestrus 3-6 year old dogs were presented to four fertile males aged 3-5 years for detection of estrus and natural insemination. At 50 and 90-120 postpartum groups of 5 dogs each were fed 0.125mg/kg bromocriptine or 0.012mg/kg cabergoline daily (in 2 doses) to induce estrus. In dogs given bromocriptine at 50 days post partum,, the time from beginning of treatment to onset of pro-estrus bleeding was ~25 3 days, but given at 90-120 days post partum, was ~31 1 days. For cabergoline, estrus began at ~27 3 and ~31 2 days, respectively. We found significant differences (P<0.01) in time to estrus and conception rates between treatments but no differences in number of puppies born. Results suggested that bromocriptine may have induced estrus in anestrous bitches sooner than cabergoline.


Key words: bromocriptine, cabergoline, estrous, induction, canine.