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OJVRTM

 Online Journal of Veterinary Research©

  Volume 11 (1) : 12 -22, 2007. Redacted extensively 2018.


Chromosomal aberrations in buffalo with brucellosis and cattle with tuberculosis

 

Ghazy AAa*, Ghazi YAb, Mahmoud KGb, Farghaly AAc

 

a Department of Parasitology and Animal Diseases, b Animal Reproduction and Artificial Insemination, c  Genetics and Cytology, Veterinary Research Division, National Research Center, Post Box 12622, 33 El-Tahrir Street, Dokki, Giza, Cairo, Egypt.

 

ABSTRACT

 

Ghazy AA, Ghazi YA, Mahmoud KG, Farghaly AA Incidence of Chromosomal aberrations in buffalo with brucellosis and cattle with tuberculosis, Onl J Vet Res., 11 (1) : 12-22, 2007. Chromosomal structural aberrations were found to be more frequent in buffaloes with brucellosis (5.40 ± 0.72) or cattle with tuberculosis (5.55 ± 0.52), than in non-infected controls (2.20 ± 0.45) and (3.11 ± 0.60), respectively. Results suggest that Brucella infected buffaloes could be screened with rose bengal and immune-chromatographic test and confirmed by specific complement fixation tests. Moreover, single cervical tuberculin test together with caudal-fold test confirmed by bacteriological culture of milk could be helpful as diagnostic tools for bovine tuberculosis in dairy cattle. Structural chromosomal aberrations in the form of fragments, gaps, breaks and deletions were significantly increased in buffaloes with brucellosis and dairy cattle with bovine tuberculosis. Thus, chromosomal abnormalities may be implicated in the pathogenesis of brucellosis and bovine tuberculosis. Genetic counseling and consideration of disease diagnosis should be an integral part of planning of control strategies.

 

 

KEYWORDS: Chromosomal aberrations; Brucellosis; Buffaloes; Bovine tuberculosis; Dairy cattle.


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