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OJVRTM
Online Journal of Veterinary Research©
Volume 19(9): 609-612, 2015.
Non-effect
of probiotic (Bifidobacterium infantis) on bone density and bone loss in male rats
Taghian Mehdi1,
Torabinejad Motaghi Ehsan2,
Najarian Mojtaba3, Ghasemi
Masumeh4.
1Department of Oral and
Maxillofacial Surgery, Mazandaran University of
Medical Science, 2Isfahan Pharmaceutical Sciences Research
Center, School of Pharmacy, Isfahan University of Medical Sciences, 3Department
Of Oral and Maxillofacial Radiology,
School of Dentistry, North Khorasan University of Medical Sciences Bojnourd, 4Department of Immunology, School of
Medicine, Medical University of Shahrekord, Iran.
ABSTRACT
Mehdi T, Ehsan TM, Mojtaba
N, Masumeh G., Non-effect of probiotic
(Bifidobacterium infantis) on bone density and bone
loss in male rats, Onl J Vet Res., 19(9): 609-612, 2015. Intestinal flora may affect bone health
and the effect of probiotic bacteria on bone density is described. Nine rats were fed ~109 Bifidobacterium infantis
probiotics daily and at 70 days were
ligated around one 1st molar. Thirty days later the animals were
euthanized, the mandibular bone removed, and bone loss assessed. Another 9
ligated rats, not fed probiotics were used as controls. Ligated teeth displayed
a significant decrease in bone density in all rats (p < 0.05). However, this
study showed no significant differences among the ligated teeth between rats
given probiotic and controls (p > 0.05). Results suggest that Bifidobacterium infantis
does not affect alveolar bone density or bone loss in ligated teeth.
Key words: Bifidobacterium infantis,
bone loss, bone density, teeth
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