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Online Journal of Veterinary Research

Volume 24 (2):94-98, 2020.

Effect of betel nut (Areca catechu), Neem (azadirachta indica) leaf and Fenbendazole against liver fluke (Fasciola spp).

Varadharajan A1, Gnanasekar R2 , Kothandaraman S3 and Sivasakthivelan P4


123Division of Animal Husbandry, 4 Department of Microbiology, Faculty of Agriculture, Annamalai University, Annamalai Nagar - 608002, Tamil Nadu, India.




Varadharajan A, Gnanasekar R , Kothandaraman S, Sivasakthivelan P., Effect of Betel nut (Areca catechu), Neem (Azadirachta indica)leaf and Fenbendazole against liver fluke (Fasciola spp), Onl J Vet Res., 24 (2):94-98, 2020. We report effect of 10 to 40% betel nut (Areca catechu) (BNE) and Neem (Azadirachta indica) leaf extracts against standard 10% Fenbendazole and 25ml agar controls on viability of adult fasciola spp. flukes. Flukes were assessed for motility, gross and microscopic changes. Compared with agar controls where flukes survived 8 hours, in those treated 10% BNE, were immobilized or killed by 0.22min, 20% at 0.07min and in 40% BNE, upon contact (0 min) but in azadirachtin only by 220, 151, and 98 min, respectively. Fenbendazole stopped motility by 0.38 min. We found marked gross and microscopic changes in flukes exposed to BNE but no effects in those kept in neem extract. Our findings suggest that BNE may be effective in controlling liver fluke.

Key-words: Betel nut, Fasciola spp, Neem leaf.