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Online Journal of Veterinary Research©
Volume 24 (1):1-6, 2020..
Effects of A. indica, N. tabacum, C. procera and T. ammi formulation and
fenbendazole on helminths, hematology and biochemistry in goats.
A. Varadharajan1, R. Gnanasekar2, S. Kothandaraman3 and P. Sivasakthivelan4
1,2,3Division of Animal Husbandry, 4Department of Microbiology, Faculty of Agriculture, Annamalai University, Annamalai Nagar – 608 002.Tamil nadu, India.
Varadharajan A, Gnanasekar R, Kothandaraman S, Sivasakthivelan P.Effects of A. indica, N. tabacum, C. procera and T. ammi formulation and fenbendazole on helminths, hematology and biochemistry in goats. Onl J Vet Res., 24 (1):1-6, 2020. Synthetic anthelminths induce parasite resistance whereas some plant extracts do not. We tested 2, 3 and 4g/kg oral formulation of crude aqueous extract of leaves of Azadirachta indica and Nicotiana tabacum, flowers of Calotropis procera and seeds of Trachyspermum ammi on nematode egg count in infested goats. Controls were goats with low egg count and those infested but given 10mg/kg fenbendazole. Treatments were repeated at 14 days. To assess toxicity, we took blood at days 0, 14 and 30 for hematology and blood biochemistry. By day 30, in goats given the formulation we detected 62% egg reduction with 2g, 69% with 3g and 73% with 4g (P < 0.05). In goats given fenbendazole egg were reduced 67% (P < 0.05). We found no significant changes in hematology or blood biochemistry.
Keywords: Gastrointestinal nematodes, Goats, Herbal formulation, Nicotianatabacum, Azadirachta indica, Calotropis procera, Trachyspermum ammi.