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Department(s) 1surgery and small animal internal medicine, Faculties of Veterinary Science, Islamic Azad University, Tehran, 2Clinical Sciences, Karaj Branch, 3Epidemiology, School of Veterinary Medicine, University of Tehran, Tehran-Iran
Gharib FZ, Aldavood SJ, Selk Ghaffari M, Mashhady Rafie S, Akbarein H., Effects of oral Propranolol and Atenolol on intraocular pressure in clinically normal dogs, Onl J Vet Res., 25(4):301-305, 2021. Glaucoma is associated with abnormal increase in intraocular pressure and treatment aims to maintain normal pressure. Groups of 5 clinically normal 15.5 to 25 kg 1 to 3 year old dogs with no ocular disease determined by Schirmer tear test (STT), applanation tonometry, slit-lamp biomicroscopy, indirect ophthalmoscopy, physical examination and complete blood counts (CBC) were given 1mg/kg oral propranolol or 1mg/kg atenolol daily for 14 days. Introcular pressure was measured by applanation tonometry at 10AM before and on days 1, 3, 5, 7 and 14. We found no significant changes between treatments. Oral Β-adrenergic blocking agents such as propranolol or atenolol appear not to affect ocular pressure of clinically normal dogs over 14 days.
Key words; propranolol , atenolol , intraocular pressure, IOP, dogs.