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OJVRTM

Online Journal of Veterinary Research ©

Volume 15 (4): 305-313, 2011. Extensively redacted 2017.


Hematology and antioxidant enzymes in malignant ovine theileriosis

 

SM Razavi1, S Nazifi2, E Rakhshandehroo1, M Ghane2

 

1Departments of Pathobiology and 2Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz, Iran

 

ABSTRACT

 

Razavi SM, Nazifi S, Rakhshandehroo E, Ghane M., Hematology and antioxidant enzymes in malignant ovine theileriosis, Online J Vet Res., 15 (4): 305-313, 2011. The effect of natural Theileria lestoquardi (hirci) infection on hematology and antioxidant enzymes in Iranian fat-tailed sheep is described. One to 2 year old sheep infected by <2%(n=14), 2-4%(n=25), and >4%(n=11) parasites, were used. Controls consisted of 10 non-infected sheep. Results revealed differences in red blood cell count (RBC), packed cell volume (PCV), mean corpuscular volume (MCV), concentration of hemoglobin and methemoglobin and SOD and GPX activity between control and diseased sheep (P<0.01).  Mean corpuscular hemoglobin concentration (MCHC) showed no difference. Increase in parasites correlated with decreased RBC (r = –0.36), PCV (r = – 0.78), hemoglobin (r = –0.77), SOD (r = –0.53) and GPX (r = –0.53) and increased methemoglobin (r = 0.37) except for sheep with <2% parasites. Parasitemia correlated with severity of anemia and hemolysis.

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Keywords: Malignant theileriosis , sheep , hematological parameters, antioxidant enzymes


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