1994-2020. All Rights Reserved. Online Journal of Veterinary Research. You may not store these pages in any form except for your own personal use. All other usage or distribution is illegal under international copyright treaties. Permission to use any of these pages in any other way besides the before mentioned must be gained in writing from the publisher. This article is exclusively copyrighted in its entirety to OJVR publications. This article may be copied once but may not be, reproduced or re-transmitted without the express permission of the editors.


Online Journal of Veterinary Research

Volume 23 (1):89-93, 2019.

Effect of oral Thymus vulgaris supplement on serum Newcastle disease vaccine antibody in Ross broilers.


Forough Talazadeh1, Mansoor Mayahi2 and Marziye Zahedzadeh3


1Associate Professor, 2Professor, 3Graduate, Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.




Talazadeh F, Mayahi M, Zahedzadeh M., Effect of oral thymus vulgaris supplement on serum Newcastle disease vaccine antibody in Ross broilers, Onl J Vet Res., 23 (1):89-93, 2019. We describe effect of a Thymus vulgaris formulation (Antibiofin) supplement given in drinking water on serum antibody response to Newcastle diseases vaccine in Ross broiler chicks. One-day old chicks were vaccinated with live Newcastle B1 vaccine intraocularly and avian Influenza-Newcastle H9N2 killed vaccine subcutaneously 9 days later. Blood samples were collected before vaccination at day 0 and 14, 21 and 28 days after for antibody titers. After vaccination, groups of 20 each were given 0.1% or 0.2% thymol in drinking water for 28 days. Twenty controls were vaccinated but not supplemented. Antibody titer against Newcastle diseases vaccine was determined by Hemagglutination Inhibition test. Compared with controls at Day 0 and day 21 we found that in chicks given 0.2% thymol antibody titers increased 21 days after vaccination ~5-10% (P < 0.05). We did not detect any effect of the formulation on immunity markers at 14 and 28 days after vaccination.


Keywords: Newcastle disease vaccine (NDV), thymol extract, immune response, broilers. Raw data provided.