Forough Talazadeh1, Mansoor Mayahi2 and Marziye Zahedzadeh3
1Associate Professor, 2Professor, 3Graduate, Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Talazadeh F, Mayahi M, Zahedzadeh M., Effect of oral thymus vulgaris supplement on serum Newcastle disease vaccine antibody in Ross broilers, Onl J Vet Res., 23 (1):89-93, 2019. We describe effect of a Thymus vulgaris formulation (Antibiofin®) supplement given in drinking water on serum antibody response to Newcastle diseases vaccine in Ross broiler chicks. One-day old chicks were vaccinated with live Newcastle B1 vaccine intraocularly and avian Influenza-Newcastle H9N2 killed vaccine subcutaneously 9 days later. Blood samples were collected before vaccination at day 0 and 14, 21 and 28 days after for antibody titers. After vaccination, groups of 20 each were given 0.1% or 0.2% thymol in drinking water for 28 days. Twenty controls were vaccinated but not supplemented. Antibody titer against Newcastle diseases vaccine was determined by Hemagglutination Inhibition test. Compared with controls at Day 0 and day 21 we found that in chicks given 0.2% thymol antibody titers increased 21 days after vaccination ~5-10% (P < 0.05). We did not detect any effect of the formulation on immunity markers at 14 and 28 days after vaccination.
Keywords: Newcastle disease vaccine (NDV), thymol extract, immune response, broilers. Raw data provided.