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Online Journal of Veterinary Research©
(Including Medical and Laboratory Research)
Volume 26 (12): 861-865, 2022.
Effect of Alhagi camelorum, Ziziphus spinachristi and Levisticum officinalis supplements
on blood glucose in male non-diabetic and diabetic Wistar rats.
Mohammadi Abbass1, Emadi ladan2, Barghi Maryam2
1Kerman University of Medical Sciences, 2School of Veterinary Medicine, University of Kerman, Iran
Abbass MN, Ladan E, Maryam B., Effect of Alhagi camelorum, Ziziphus spinachristi and Levisticum officinalis supplements on blood glucose in male non-diabetic and diabetic Wistar rats, Onl J Vet Res., 26 (12): 861-865, 2022. Authors describe effect of methanolic extracts of alhagi camelorum, ziziphus spinachristi and levisticum officinal on blood glucose in normal and streptozotocin diabetic male Wistar rats. Rats were fasted 15h prior to experiments and 1ml of herbal extracts gavaged by stomach tube. Blood glucose was determined by glucometer at 0, 30, 60 and 120min after treatments. Diabetes was induced by 60mg/kg Streptozotocin. Then 5 groups of 6 non-diabetic and 6 diabetic rats each were gavaged 2g/kg maltose and 50mg/kg acarbose (1), with 1000mg/kg alhagiacamelorum (2), Ziziphusspina Christi (3) and Levisticum officinal (4) Controls were gavaged only 2g/kg maltose (5). Compared with controls, Levisticum officinal gavage had no effect on glucose in non-diabetic rats whereas Alhagiaca melorum and Ziziphus spina reduced it ~16-23% (P < 0.05). In diabetic rats, these extracts reduced glucose ~14-21%. Our results suggest that these plants extracts could ameliorate rises in blood sugar in diabetic rats.
Keywords: Diabetes mellitus, Alpha glucosidase, Alhagia camelorum, Ziziphus spina, levisticum officinal, rats.