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OJVRTM

Online Journal of Veterinary Research©

 (Including Medical and Laboratory Research)

Established 1994

ISSN 1328-925X

 

Volume 26 (4): 255-261, 2022.

 

Effect of Vitamin C on oxidation in adrenals of rats exposed to mobile radio waves.

 

Abolfazl Akbari, Gholamali Jelodar, Saeed Nazifi.

 

School of Veterinary Medicine, Shiraz University, Shiraz 71345, Iran

 

ABSTRACT

 

Akbari A, Jelodar G, Nazifi S., Effect of Vitamin C on oxidation in adrenals of rats exposed to mobile radio waves, Onl J Vet Res., 26 (4): 255-261, 2022. Radio frequency waves (RFW) generated by base transceiver stations (BTS) have been reported to affect endocrine function, possibly by oxidative stress. We report effect of radiofrequency wave (RFW)-induced oxidation in adrenal gland and vitamin C supplement on glutathione peroxidase (GPx), superoxide dismutase (SOD) catalase (CAT) and malondialdehyde (MDA) in 4 groups of 8 adult male Sprague-Dawley rats gavaged daily for 45 days with (1) 200mg/kg L-ascorbic acid 200 mg/kg and then exposed to 900MHz RFW 4h/day (1) given only vitamin C (2) controls or not exposed but treated (3). Other non-exposed controls were given distilled water (4). At necropsy during day 45 adrenals were excised and stored at -70°C for antioxidant enzymes and MDA. Compared with controls, in rats exposed to RFW, vitamin C boosted SOD 41%, GPX 40% and CAT 32% but reduced MDA 46% (P < 0.05).

 

Key Words: Radiofrequency wave, BTS, Oxidative stress, Vitamin C, Adrenal gland.

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