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OJVRTM
Online Journal of
Veterinary Research©
Volume 19(3): 155-161,
2015
Malignant adenomyo-epithelioma in a feline mammary
gland
De Campos CB1,2 DVM Ms, Gamba CO2
DVM Ms, Damasceno KA2 DVM Ms, Lavalle GE3 PhD, Cassali GD2
DVM Ms PhD
1Veterinary Clinic and
Surgery, School of Agricultural and Veterinary Sciences, Sao Paulo State
University, 2Department(s)
of General Pathology, Biological Science Institute, 3Veterinary Clinic and Surgery, Federal University of Minas Gerais, Belo Horizonte, Brazil.
ABSTRACT
De
Campos CB, Gamba CO, Damasceno
KA, Lavalle GE, Cassali
GD., Malignant adenomyo-epithelioma in a feline
mammary gland, Onl J Vet Res., 19(3): 155-161, 2015. Mammary
neoplasms are the third most frequent tumor in felines. We describe clinical, histopathological, and immuno-histochemical
findings from a malignant adenomyo-epithelioma (MA) from
a domestic queen. The cat presented with mammary masses and underwent radical
unilateral mastectomy followed by chemotherapy. The tumor recurred and the
animal survived 125 days but then died. Microscopy revealed a highly cellular
malignant myoepithelial solid cell proliferation
pattern with moderate pleomorphism and malignant
epithelial proliferation in a tubular and papillary arrangement. The myoepithelial nature of the neoplastic cells was confirmed by
p63 target antigen clone test. Histo-pathological and immun0-histochemical results together
with histological similarity between women and feline tumors suggested a
diagnosis of MA.
Key-Words: feline, mammary gland, neoplasm, malignant adenomyoepithelioma.
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